WIUM Tristates Public Radio

"Stud Dames" Spread U.S. Cow Genetics Far and Wide

May 18, 2015

Panda, standing six feet tall and weighing almost a ton, is everything a show cow should be: broad-backed and round-rumped, with sturdy legs holding up her heft. Her hide -- thick and black, with splotches of creamy white -- fits her name.  "She's a big time cow," said Dan Byers, owner of Byers Premium Cattle, Inc. "She's a freak of nature is what she is."

Because of her impeccable physique, Panda’s descendants sell for a high price. Byers, an elite-cattle breeder in Roseville, owns several of Panda’s daughters. He sold one of her grand-calves last year for $10,000 to a family in Oklahoma that shows cattle at state fairs and national competitions.

Cows take about nine months to carry a calf to term. At eight years old, Panda should have seven calves. But in the 1970s, American cattlemen began bucking the reins of nature’s limitations by performing a procedure called embryo transfer, or E.T., as it’s referred to in the industry.

Panda is held in a cattle chute during the embryo-harvesting procedure. Dr. Pugh has collected her embryos an estimated 35-40 times, resulting in hundreds of embryos.
Credit Abby Wendle

Now, elite-cattle breeders and commercial beef and dairy producers use E.T. to reproduce dozens of calves a year from their genetically superior heifers, who never actually have to birth a single calf. Surrogates carry the embryos to term.

The process can be time consuming and costly, but Byers, who has bred his genetically superior cattle this way for six years, said it can pay off in the long run.

"There’s definitely a lot of work that goes into it, compared to just raising them normally," Byers said. "But ultimately when the cattle are good, then it should hopefully be more for your bottom dollar."

Embryo transfer, which maximizes the number of offspring a female can reproduce, was first successfully reported in rabbits in 1890. Walter Heape, a pioneer in reproductive biology from England, collected embryos from a black rabbit and inserted them into a white rabbit. A month later, the white rabbit gave birth to a litter of black bunnies. The first E.T. calf, born in Wisconsin, came along in 1951.

Maximizing Effort

E.T. entails several steps.

  • First, the cow’s owner injects her with a series of hormones so she’ll produce multiple eggs.
  • Next, she’s bred by a choice stud bull. The fertilized eggs, or embryos, are complete genetic packages carrying the bull and dame cow’s traits. Cows that undergo E.T. hormone therapy produce anywhere from a few embryos to 80 or 90 at once.
  • Then, a livestock vet performs the "embryo flush," the procedure used to get out all those invisible genetic packages.

On a windy afternoon, Dr. Michael Pugh, owner of Westwood Embryo Services, turned Panda’s cattle barn in rural Illinois into an impromptu laboratory. Petri dishes and microscopes lined the workbench and boxes of needles and catheters crowded the floor. Pugh was stationed at Panda’s rear donning boots, overalls, and a plastic glove up to his shoulder. He stuck Panda with an epidural, then slid his entire arm inside.

Dr. Michael Pugh owns Westwood Embryo Services in Waverly, Iowa. Pugh travels around the Midwest collecting and transferring bovine embryos.
Credit Abby Wendle

"It seems so routine to me now. When you just reach in a cow and do what you got to do," Pugh chuckled. "And she’s kind of an old pro. She just walked in here and stood."

Pugh massaged saline solution around Panda’s uterus, helping the embryos release from her ovaries and slip through a catheter into a receptacle slightly fancier than a Dixie cup. He peered through a microscope into the fluid and counted them, ranking embryos from the highest grade, “transferable,” to the lowest, “degenerates.”

"The best part for me is when you go look at the embryos in a dish and you realize number one, what their value is for the client," Pugh said. "And then that, you know, those are calves right there."

Panda produced six good embryos that Pugh sealed in glass straws and froze in tanks of liquid nitrogen. They took a short trip down the road to a second barn where they will be inserted into less valuable, "surrogate mother" cows that will carry them to birth.

E.T. is one of several reproductive technologies ranchers use to manage the genetics of their herd. Artificial insemination and in vitro fertilization are common practices, in addition to being able to select for the sex of the calf and test an embryo's DNA for undesirable traits or diseases.

Kyle Greiman, Dr. Pugh’s lab technician, peers through a microscope, counting and rating embryos on a scale of “transferable” quality to “degenerate.”
Credit Abby Wendle

When using E.T., there is the risk of inbreeding. If a rancher chooses to only breed offspring from a single cow, they can limit the herd’s genetic diversity, potentially making them more vulnerable to disease.

“I think we have to be careful about how far we push the envelope,” Pugh said.

Paradoxically, E.T. can also help preserve genetic diversity. As Harvest’s Luke Runyon reported, the USDA stockpiles embryos from a wide variety of livestock breeds in Fort Collins, CO.

The Embryo Export Industry

U.S. beef and dairy genetics are in-demand all over the world. Producers use E.T. to collect and export embryos globally: full-bred beef embryos fly to Australia and Brazil; high-end dairy embryos voyage to Japan and China. In-country they’re implanted in local surrogates and born not to produce hamburgers and milkshakes, but to become the matriarchs and patriarchs of a burgeoning cattle industry.

"You don’t want to eat them," said Matthew Wheeler, professor of animal sciences at the University of Illinois. "They’re too valuable."

Dr. Matthew Wheeler, professor of animal sciences at the University of Illinois, freezes bovine embryos in tanks of liquid nitrogen. He has some embryos that date back to the 1980s.
Credit Abby Wendle

The U.S. is currently the leader in cattle embryo exports, shipping off about 15,000 embryos a year, according to the American Embryo Transfer Association (AETA), the trade group that certifies and tracks E.T. procedures. The AETA’s numbers are a rough estimate, given that E.T. service providers voluntarily submit data on an annual basis and many businesses resist sharing information for fear competitors will encroach on their market.

Wheeler, who’s been involved in the embryo business since the 1970s, says U.S. genetics are a hot commodity -- the cream of the crop have sold for half a million bucks -- because American cows are milk and meat production machines.

"You can just look at U.S. dairy cattle and see how much more they're producing," Wheeler said. "It doesn't take a rocket scientist to say, well, America’s doing something right."

American Angus cattle gain more beef per pound of animal and U.S. Holsteins can out-milk pretty much any cow on earth. That’s partly because America has plenty of land, water, and feed. But Wheeler said it’s also because the cattle have been bred that way for more than a century.

And the U.S. herd is getting more efficient all the time. Wheeler said that  since 1940 producers have decreased the number of dairy cattle by half, while increasing milk production by two-and-a-half times. He said other countries are eager to tap into America's successful gene pool.

"We're not pushing our genetics on them.  They're coming to us," he said.

While America still ships whole animals overseas, it's easier to load a bunch of embryos on a 747 than it is to pack up a herd. Embryos are also less susceptible to disease than cows because they spend nine months in a native cow's womb, soaking up her antibodies and developing an immune system suited to the local environment.

Wheeler, who used to be in the business of selling high-end genetics, is now working with his lab at the University of Illinois to develop a decent, low cost embryo for countries that struggle to produce enough milk. The lab has partnerships with scientists, cattle producers, and ministers of agriculture in several countries including Sri Lanka, Thailand, the Dominican Republic, Panama, Sierra Leone, Libya, and Rwanda.

Panda produced six high quality embryos. Embryos typically sell for hundreds of dollars.
Credit Kyle Greiman

"Rwanda had a civil war where many of the cattle were also killed in the genocide," Wheeler said. "So they're interested in redeveloping their cattle herd, and they want to do it with better genetics."

Many of these countries sit along the earth’s tropical belt, a climate too hot for full-bred Angus and Holsteins. The embryos Wheeler ships are typically cross-bred with Bos indicus breeds, cows that are native to these countries. Bos indicus cattle have a hump on their back, floppy ears, and flabby necks to help keep off the flies and release extra heat.

Wheeler said sometimes local farmers hesitate to adopt the technology.

"They’re farmers, so they’re skeptical," he said.

"But the farmers that have animals old enough to milk and they’re producing more milk and getting more money in their pocket, they’re really enthusiastic to have us come back."

Birthing an E.T. Calf

Back at Dan Byers' farm in western Illinois, expectant cows pace around the pasture. 140 of them are pregnant, the majority with embryos from a handful of donors.

Looking out over the field, Byers spotted surrogate mother No. 4030 clearly getting ready to give birth.

"You can tell by the way she’s pacing that something’s going on with her," he said.

Surrogate mother No.4030 was the second cow who had to undergo a C-section birth on a recent day. Surrogate mothers can sometimes have bodies too small to properly handle the size of the embryo calf they birth.
Credit Abby Wendle

On this occasion, the embryo calf is coming out backwards, so Byers called the vet. The men used a crank to try and muscle the calf out. The cow’s knees buckled with pain. After a few more attempts, they opted for a C-section. The vet made a large incision in her side, tugged, and the newborn calf slid out.

Byers carried her to a bed of straw, checked her heart beat, and sprinkled her with sweet molasses powder, which will help prompt her mother to lick her clean, a maternal instinct sometimes silenced by surgical birth.

If all goes according to Byers’ plan, the E.T. calf will grow up to become another American show cow champion.